Layer shift like that is caused by one of the axes not working correctly, either because the nozzle is impacting the part during a move or the axis is hitting something. I would check that your axes both move smoothly and with the same amount of force. If you find one doesn't move as freely as the other, it may be that you have a mechanical issue causing the layer shift other than a nozzle impact. I would try a different print to see if you get the same behavior. If so, open a support ticket since you will need to get into the mechanical parts to determine what is happening.
If it is only that print my guess is that there is a feature that is causing warping and you are getting nozzle strikes during printing and not just rapids. Nozzle hop will help prevent nozzle strikes while moving rapidly but will not solve nozzle strikes that happen during printing.
You should also check that your nozzle isn't leaking as this will allow a buildup of material on the head that can cause this issue.